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Chemoselective Nucleophilic α-Amination of Amides


Chemoselective Nucleophilic α-Amination of Amides


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von: Miran Lemmerer

53,49 €

Verlag: Spektrum Akademischer Verlag bei Elsevier
Format: PDF
Veröffentl.: 03.04.2020
ISBN/EAN: 9783658300203
Sprache: englisch

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Beschreibungen

<p>α-Amino carbonyl compounds are omnipresent in all living organisms, making their selective synthesis highly sought after. However, the synthesis of α-amino amides, a subclass of α-amino carbonyls, in the presence of other carbonyls is usually challenging, due to the required harsh conditions. Miran Lemmerer expands a novel chemoselective approach for the synthesis of these intriguing molecules together with Univ.-Prof. Dr. Nuno Maulide’s team.</p>

<p><b>The Author:</b></p><p><b>Miran Lemmerer</b> is currently pursuing his PhD studies under supervision of Prof. Dr. Nuno Maulide at the Department of Organic Chemistry, University of Vienna, Austria.&nbsp;<br></p>
Traditional Umpolung Reactions in Organic Chemistry.- Insight into Electrophilic Amide Activation.- Results and Discussion of a New α-Amination Method via Umpolung of Amides.- α-Arylation of Carbonlys via a Smiles Rearrangement.
<b>Miran Lemmerer</b> is currently pursuing his PhD studies under supervision of Prof. Dr. Nuno Maulide at the Department of Organic Chemistry, University of Vienna, Austria.&nbsp;
α-Amino carbonyl compounds are omnipresent in all living organisms, making their selective synthesis highly sought after. However, the synthesis of α-amino amides, a subclass of α-amino carbonyls, in the presence of other carbonyls is usually challenging, due to the required harsh conditions. Miran Lemmerer expands a novel chemoselective approach for the synthesis of these intriguing molecules together with Univ.-Prof. Dr. Nuno Maulide’s team.<div><br><div><b>Contents</b></div><div><ul><li>Traditional Umpolung Reactions in Organic Chemistry</li><li>Insight into Electrophilic Amide Activation</li><li>Results and Discussion of a New α-Amination Method via Umpolung of Amides</li><li>α-Arylation of Carbonlys via a Smiles Rearrangement</li></ul></div><div><b>Target Groups</b></div><div>Scientists and students in the field of organic chemistry, especially in methodology development</div><div><br></div><div><b>The Author</b></div><div><b>Miran Lemmerer</b> is currently pursuing his PhD studies under supervision of Prof. Dr. Nuno Maulide at the Department of Organic Chemistry, University of Vienna, Austria.&nbsp;</div><div><br></div></div>
Organic Synthesis via Umpolung and Rearrangement

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